Product Introduction
DESU® DCPA 60Ⅱ is a medium-particle crystalline anhydrous dibasic calcium phosphate designed as a premier direct-compression filler for oral solid dosage forms. It delivers exceptional powder flow for high-speed tableting operations and its high bulk density enables the production of smaller tablets. Its neutral pH provides a stabilizing alkaline microenvironment for acid-labile APIs, while its low water absorption ensures minimal moisture interaction with sensitive actives. The crystalline cluster morphology combined with brittle-fracture deformation behavior gives DESU® DCPA 60Ⅱ low sensitivity to lubrication variations, enabling reliable scale-up from R&D to commercial manufacturing. When blended with microcrystalline cellulose, it achieves significantly enhanced compressibility for demanding tablet formulations.
Product Feature
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Medium crystalline structure with optimal particle size
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High bulk density for tablet miniaturization
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Excellent flowability for high-speed direct compression
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Neutral pH for API stabilization
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Low water absorption — ideal for moisture-sensitive drugs
- Optimized for direct compression processes
- Synergistic performance with microcrystalline cellulose
Product Application
DESU® DCPA 60Ⅱ is the preferred grade for direct compression formulations of moisture-sensitive and acid-labile APIs. Its unique combination of high bulk density and neutral pH makes it especially valuable for miniaturizing tablet size while providing a stabilizing microenvironment that protects the API from degradation. The exceptional powder flow characteristics support commercial-scale high-speed tableting, and when co-processed with microcrystalline cellulose, it produces tablets with high hardness, low friability, and suitable disintegration times. It serves as an ideal platform for the development of immediate-release formulations of poorly soluble drugs requiring a stable, low-moisture excipient.
Product Specification
| Appearance |
Median particle size (μm) |
Bulk Density (g/mL)
|
|
White crystalline clusters
|
65-89 |
~ 1.17 |
Packaging
- 20-foot container can hold 10 to 11 metric tons of DESU® DCPA 60Ⅱ.
- Standard packaging of 20/25 kg per bag.