Product Introduction
DESU® DCPA 12Ⅱ is a fine-particle crystalline anhydrous dibasic calcium phosphate specifically engineered for wet granulation and dry granulation processes. Its small particle size provides a large specific surface area that promotes uniform binder distribution and optimal granule formation. Its neutral pH creates a stable micro-environment for APIs sensitive to acidic or alkaline conditions, while its low water absorption minimizes moisture exposure in humidity-sensitive formulations. As a brittle-fracture excipient, DESU® DCPA 12Ⅱ exhibits low sensitivity to over-lubrication, facilitating smooth scale-up from lab to commercial production. When blended with microcrystalline cellulose, it delivers significantly improved compressibility for direct compression applications.
Product Feature
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Fine crystalline structure with small particle size
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Neutral pH for broad API compatibility
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Low water absorption — ideal for moisture-sensitive drugs
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Optimized for wet granulation and dry granulation
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Low sensitivity to lubrication variations
- Improved compressibility when co-processed with MCC
- High batch-to-batch consistency
Product Application
DESU® DCPA 12Ⅱ is predominantly used in wet granulation and dry granulation processes for tablets requiring fine particle distribution and a neutral pH microenvironment. Its low hygroscopicity makes it particularly suitable for moisture-sensitive APIs, while its small particle size provides excellent content uniformity for low-dose formulations. In combination with microcrystalline cellulose, DESU® DCPA 12Ⅱ can be effectively utilized for direct compression, delivering robust tablet hardness while maintaining API protection benefits. It is a reliable choice for developers seeking a stable, low-moisture excipient for challenging formulations.
Product Specification
| Appearance |
Median particle size (μm) |
Bulk Density (g/mL)
|
|
White crystalline powder
|
11-19 |
~ 0.84 |
Packaging
- 20-foot container can hold 10 to 11 metric tons of DESU® DCPA 12Ⅱ.
- Standard packaging of 20/25 kg per bag.