Product Introduction
DESU® Mannitol 150SD is manufactured through a proprietary spray-drying process that yields porous, free-flowing spherical agglomerates. The optimized particle size distribution provides an ideal combination of flow consistency and compression behavior, ensuring uniform die filling and reliable tablet hardness on high-speed rotary presses. With tightly controlled moisture and reducing sugar levels, it offers excellent chemical stability for sensitive formulations. Its brittle deformation profile under compression guarantees low sensitivity to lubricant over-mixing, supporting robust and reproducible direct compression processes.
Product Features
- Low Lubricant Sensitivity
- Low Reducing Sugar
- Superior Flowability
- Excellent Compressibility
- Low Hygroscopicity
Product Applications
DESU® Mannitol 150SD offers balanced performance for a wide range of conventional oral solid dosage direct compression applications, particularly for high-volume manufacturing on high-speed rotary presses that require stable flow and consistent compressibility. Its low hygroscopicity and minimal reducing sugar content protect the long-term stability of moisture-sensitive and degradation-prone APIs, while its well-controlled particle size distribution also makes it suitable for pre-blending in both dry and wet granulation processes, reducing the need for process re-optimization. The excipient’s refreshing sweetness also positions it as a preferred option for orodispersible and chewable tablets with strict sensory requirements.
Product Specification
| Type |
Median particle size (μm) |
Reducing Sugars (%) |
| Spray-dried |
100-135 |
≤ 0.015 |
Packaging
- 20-foot container can hold 10 to 11 metric tons of DESU® Mannitol 150SD.
- Standard packaging of 20/25 kg per bag.