DESU® Mannitol 200SD

DESU® Mannitol 200SD is a spray-dried direct compaction grade of D-mannitol with a median particle size of 135-200 μm. Its higher specific surface area ensures exceptional compressibility, maintaining tablet hardness and stability even in high-API-load formulations.

  • Item No :

    DESU® Mannitol
  • Product Origin :

    CHINA
  • Shipping Port :

    SHANG HAI
  • Payment :

    TT/LC
  • Weight :

    20/25KG
  • Order(MOQ) :

    100KG

Product Introduction

 

DESU® Mannitol 200SD is produced via an advanced spray-drying process forming porous, spherical agglomerates with a large specific surface area. This morphology promotes strong inter-particle mechanical interlocking during compression, enabling robust tablet formation even when the active ingredient constitutes up to 30% of the formulation. Moisture and reducing sugar are strictly controlled to protect moisture-sensitive and chemically reactive APIs. The product's dominant brittle deformation mechanism makes it highly tolerant to lubricant mixing time variations, providing a broad and stable processing window for demanding direct compression applications.
 
 

Product Features

 

  • Low Lubricant Sensitivity
  • Low Reducing Sugar
  • Superior Flowability
  • Excellent Compressibility
  • Low Hygroscopicity
  • High Specific Surface Area

 

 

Product Applications

 
DESU® Mannitol 200SD is optimized for challenging, high-API-load formulations, maintaining excellent tablet hardness and structural integrity even when active ingredients account for up to 30% of the total formulation weight. It is fully compatible with high-speed direct compression, dry granulation, and wet granulation workflows, while its low hygroscopicity and reduced reducing sugar levels safeguard moisture-sensitive, oxidizable APIs such as vitamin C against degradation during storage. The ingredient’s naturally cool, sweet profile also meets the sensory demands of orodispersible and chewable tablets, making it a versatile choice for complex formulation development.
 
 

Product Specification

 

Type Median particle size (μm) Reducing Sugars (%)
Spray-dried 135-200 ≤ 0.015

 

 

Packaging

 

  • 20-foot container can hold 10 to 11 metric tons of DESU® Mannitol 200SD.
  • Standard packaging of 20/25 kg per bag.

 

 
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