DESU® Microcrystalline Cellulose PH-112

DESU® Microcrystalline Cellulose PH-112 is an ultra-low-moisture microcrystalline cellulose grade with a median particle size of 100 μm and moisture content ≤ 1.5%. It combines balanced flow and compactability with ultra-low water levels, serving as an ideal filler and binder for moisture-sensitive APIs in direct compression and dry granulation.

  • Item No :

    DESU® MCC
  • Product Origin :

    CHINA
  • Shipping Port :

    SHANG HAI
  • Payment :

    TT/LC
  • Weight :

    20/25KG
  • Order(MOQ) :

    100KG

Product Introduction

 

DESU® Microcrystalline Cellulose PH-112 is produced via Westpoint's independent patented spray-drying technology platform, which precisely regulates moisture, particle morphology, particle size distribution, and pore structure. Multi-batch COA data confirms excellent inter-batch consistency, with moisture consistently maintained at 0.3-0.6%. The grade's moisture content is more than 80% lower than conventional MCC, providing a reliable low-water excipient solution for moisture-sensitive APIs such as vildagliptin and clopidogrel bisulfate.

 

 

Product Feature

 

  • Ultra-Low Moisture Content
  • Balanced Particle Size
  • Excellent Inter-Batch Consistency
  • Superior Disintegration at Low Moisture
  • Spray-Dried Porous Structure
  • Pharmacopoeia Compliant
  • Moisture-Sensitive API Solution

 

 

Product Application

 

DESU® MCC PH-112 is predominantly applied in direct compression and dry granulation tablet formulations for highly moisture-sensitive APIs. Its ultra-low moisture profile effectively mitigates API hydrolysis and stability risks that would arise with standard MCC grades, while its balanced particle size ensures both adequate flow for die filling and sufficient compressibility for tablet formation. In direct compression of vildagliptin tablets, PH-112 delivered friability below 0.2% and disintegration performance comparable to or better than international benchmarks, with 30-minute cumulative dissolution exceeding 85% and f2 similarity >50. In dry granulation of clopidogrel bisulfate tablets, PH-112 met all compendial requirements for hardness, disintegration, and friability. These validated applications demonstrate that PH-112 is a dependable excipient choice for formulators developing moisture-critical oral solid dosage forms.

 

 

Product Specification

 

Median particle size (μm) Bulk density (g/ml) Moisture (%)
100 0.26-0.36 ≤ 1.5

 

 

Packaging

 

  • 20-foot container can hold 10 to 11 metric tons of DESU® MCC PH-112.
  • Standard packaging of 20 kg per bag.

 

 

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