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DESU® Microcrystalline Cellulose PH-200LM is an ultra-low-moisture, super-flowable microcrystalline cellulose grade with a median particle size of 180 μm and moisture content ≤ 1.5%. It combines spherical particle morphology, exceptional flow, and minimal water content, serving as a premium filler and dry binder for poorly flowing, moisture-sensitive APIs in high-speed direct compression.
Item No :
DESU® MCCProduct Origin :
CHINAShipping Port :
SHANG HAIPayment :
TT/LCWeight :
20/25KGOrder(MOQ) :
100KGProduct Introduction
DESU® Microcrystalline Cellulose PH-200LM is manufactured through Westpoint's spray-drying process, yielding approximately spherical, large-particle MCC with a near-monodisperse size distribution. The "LM" designation signifies its ultra-low moisture profile, which, combined with the super-flow characteristics inherited from PH-200, makes it uniquely suited to formulations where both flow and moisture control are critical constraints. The grade exhibits a bulk density of 0.30-0.38 g/ml and median particle size of 180 μm. Like other DESU® MCC grades, PH-200LM is produced under GMP-compliant systems and conforms to ChP, USP, EP, and JP standards. Its porous spherical particles undergo plastic deformation under compression, forming strong hydrogen bonds that deliver adequate tablet mechanical strength, while the large particle size ensures exceptional flow behavior for stable die filling and minimal weight variation in high-speed tableting.
Product Feature
Product Application
DESU® MCC PH-200LM is primarily utilized in high-speed direct compression tablet manufacturing where the formulation presents two simultaneous challenges: poor powder flow and API moisture sensitivity. Its large, approximately spherical particles deliver super-flow behavior that maintains consistent die filling and minimal tablet weight variation even at press speeds exceeding 40,000 tablets per hour, while its ultra-low moisture content prevents water-induced degradation of sensitive APIs. This dual-function profile makes PH-200LM especially valuable for commercial-scale production of tablets containing moisture-labile actives that also require high manufacturing throughput. The grade's porous structure supports capillary water penetration and effective disintegration post-compression, ensuring that the benefits of low moisture and superior flow do not come at the expense of drug release performance. For formulation teams developing high-volume oral solid dosage forms with moisture-sensitive APIs, PH-200LM offers a single-excipient solution that addresses both process robustness and product stability.
Product Specification
| Median particle size (μm) | Bulk density (g/ml) | Moisture (%) |
|---|---|---|
| 180 | 0.30-0.38 | ≤ 1.5 |
Packaging
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