Product Introduction
DESU® Mannitol 25C is a crystalline mannitol produced through a secondary crystallization process. The crystal surface features attached micro-crystals that increase roughness and specific surface area, enhancing particle-to-particle binding during granulation and tableting. Strictly controlled for particle size distribution and impurity levels, it offers low hygroscopicity and excellent chemical inertness. This fine-grade crystalline mannitol is specifically designed for wet granulation, dry granulation, and fluid bed granulation, where finer particles improve granule formation and content uniformity.
Product Feature
- Secondary Crystallization Structure
Product Application
DESU® Mannitol 25C is purpose-designed for granulation-based manufacturing processes, delivering reliable performance in wet granulation, dry granulation, and fluid bed granulation workflows. Its fine, tightly controlled particle size distribution improves granule formation efficiency and uniformity, supporting consistent content uniformity in finished solid dosage forms. The low-hygroscopicity profile makes it suitable for formulations with moisture-sensitive APIs, while it also functions as an effective matrix support material for lyophilized formulations to preserve the appearance and structural integrity of freeze-dried products. Its pleasant, cool sweetness further makes it a strong fit for chewable and orodispersible tablets that require an appealing sensory profile.
Product Specification
| Type |
Median particle size (μm) |
Moisture (%) |
| Crystalline |
>75: not more than 10% |
≤ 0.5 |
Packaging
- 20-foot container can hold 10 to 11 metric tons of DESU® Mannitol 25C.
- Standard packaging of 20/25 kg per bag.