Product Introduction
DESU® Mannitol 50C is produced via a secondary crystallization process that creates crystalline particles with attached micro-crystals on the surface, increasing roughness and specific surface area for enhanced binding. The carefully controlled particle size distribution ensures consistent granule formation and optimal compression behavior in various granulation methods. With low hygroscopicity and minimal impurity levels, it provides excellent chemical stability for sensitive formulations. When combined with microcrystalline cellulose, it demonstrates strong synergistic compressibility, making it a versatile choice for demanding tablet formulations.
Product Feature
Product Application
DESU® Mannitol 50C delivers robust performance across all common granulation processes, including wet, dry, and fluid bed granulation, with surface-attached microcrystals that enhance inter-particle binding to improve granule strength and final tablet mechanical integrity. It demonstrates strong synergistic compressibility when blended with microcrystalline cellulose, making it suitable for challenging formulations that require additional binding support. Its low hygroscopicity and chemical inertness protect the stability of moisture-sensitive and degradation-prone APIs, while its refreshing sweet taste suits orodispersible and chewable tablets with sensory requirements. It can also serve as a reliable matrix support for lyophilized formulations to maintain product structure and appearance.
Product Specification
| Type |
Median particle size (μm) |
Moisture (%) |
| Crystalline |
> 250: not more than 5%;
> 100: not more than 25%;
> 20: at least 55%
|
≤ 0.5 |
Packaging
- 20-foot container can hold 10 to 11 metric tons of DESU® Mannitol 50C.
- Standard packaging of 20/25 kg per bag.