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OPACT® LPC

OPACT® LPC is a co-processed pharmaceutical excipient combining lactose monohydrate, povidone, and crospovidone into a single free-flowing premix. Engineered for direct compression and hard capsule filling, it integrates filler, binder, and disintegrant functions in one standardized system, helping pharmaceutical manufacturers streamline formulation and accelerate tablet production.

  • Item No :

    OPACT® LPC

  • Product Origin :

    CHINA

  • Shipping Port :

    SHANG HAI

  • Payment :

    TT/LC

  • Weight :

    20/25KG

  • Order(MOQ) :

    100KG
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Product Introduction

 

OPACT® LPC (Lactose, Povidone and Crospovidone Direct Compressing Premix Excipients) is a white to off-white, odorless, free-flowing granular premix developed by Westpoint Pharma for modern direct compression (DC) tableting and hard capsule filling. The premix contains lactose monohydrate as the filler, povidone as the binder, and crospovidone as the disintegrant, in a composition aligned with internationally established direct compression premix standards. Through co-processing, the three components are integrated into a unified particulate system rather than a simple physical blend, giving the excipient enhanced flowability, compressibility, and disintegration performance compared with conventional mono-excellent materials.

 

 

Product Feature

 

  • All-in-One Functionality
  • Excellent Flowability​
  • Superior Compressibility
  • Rapid Disintegration
  • Low Hygroscopicity
  • Simplified Formulation
  • Consistent Batches
  • Customizable Specification

 

 

Product Application

 

OPACT® LPC is primarily designed for direct compression tableting and hard capsule filling in pharmaceutical and nutraceutical manufacturing. As a ready-to-use premix, it is especially valuable in generic R&D and process iteration where a filler, binder, and disintegrant must coexist — formulators can replace three separate excipients with one standardized material, dramatically shortening development cycles and reducing production costs. In innovative drug programs, OPACT® LPC enables rapid formulation advancement during the IND phase for fast proof-of-concept tableting or capsule filling, and continues to deliver commercial-scale benefits in NDA and post-marketing stages by lowering tech-transfer risk and simplifying supply chain management. The premix is also compatible with dry granulation and, where necessary, wet granulation processes, making it a versatile platform excipient for oral solid dosage forms ranging from conventional immediate-release tablets to film-coated tablets.

 

 

Product Specification

 

Composition Particle Size Distribution Bulk Density (g/ml)

Lactose Monohydrate: 91.1- 94.9%; 

Povidone: 3.0-4.0%; 

Crospovidone: 3.0-4.0%

>30 mesh: NMT 15%;

<80 mesh: NMT 55%

 0.45-0.65

 

 

Packaging

 

  • 20-foot container can hold 10 to 11 metric tons of OPACT® LPC.
  • Standard packaging of 20/25 kg per bag.

 

 

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