OPACT® Starch Lactose is a co‑processed direct compression excipient manufactured by spray‑drying a composite of approximately 85% α‑lactose monohydrate and 15% maize starch. It is specifically designed for tablet and capsule formulation, providing excellent flowability, superior compressibility, and rapid disintegration independent of tablet hardness.
Item No :
OPACT® Starch LactoseProduct Origin :
CHINAShipping Port :
SHANG HAIPayment :
TT/LCWeight :
20/25KGOrder(MOQ) :
100KG
OPACT® Starch Lactose is a high‑performance pharmaceutical excipient developed through a proprietary spray‑drying process that intimately combines α‑lactose monohydrate with maize starch. This co‑processing creates a synergistic structure that delivers outstanding powder flow, remarkable compressibility, and fast, hardness‑independent disintegration. The material exhibits both brittle and plastic deformation characteristics, making it highly versatile across multiple tablet manufacturing processes. Its hydrophilic nature enhances the dissolution and release profile of active pharmaceutical ingredients, while its resistance to over‑lubrication ensures consistent tablet quality even under varying lubricant conditions.
OPACT® Starch Lactose is primarily engineered for orally disintegrating tablets (ODT) and dispersible tablets, where its rapid, hardness‑independent disintegration delivers a pleasant patient experience with disintegration times consistently below 3 minutes even at elevated tablet hardness. Its exceptional compressibility and free‑flowing nature make it an ideal filler‑binder for direct compression tablets across a wide range of therapeutic categories, including cardiovascular, respiratory, gastrointestinal, and endocrine medications. For formulations requiring dry granulation, the material's combined brittle and plastic deformation properties ensure robust ribbon formation and subsequent tablet strength. Beyond conventional pharmaceuticals, OPACT® Starch Lactose is equally well suited for hard capsule filling, chewable tablets, and compressed nutraceutical products such as dietary supplements and pressed candies, offering formulators a single, multifunctional excipient that simplifies composition and streamlines production.
| Composition | Loss on Drying (%) | Bulk Density (g/ml) |
|---|---|---|
|
~85% α‑Lactose Monohydrate; ~15% Maize Starch |
≤ 4.0 | 0.45-0.65 |