OPACT® Cornstarch Mannitol

OPACT® Cornstarch Mannitol is a co-processed pharmaceutical excipient manufactured by spray drying approximately 80% mannitol with 20% corn starch. It is designed as a direct-compression filler for orally disintegrating tablets and chewable tablets, delivering excellent powder flow, compressibility, and rapid disintegration.

  • Item No :

    OPACT® Cornstarch Mannitol
  • Product Origin :

    CHINA
  • Shipping Port :

    SHANG HAI
  • Payment :

    TT/LC
  • Weight :

    20/25KG
  • Order(MOQ) :

    100KG

Product Introduction

 

OPACT® Cornstarch Mannitol is a high-functionality co-processed excipient developed by Westpoint Pharma through a proprietary spray-drying process. By combining mannitol and corn starch at the sub-particle level, it forms porous spherical granules that integrate the functions of filler, disintegrant, and flavoring agent in a single ingredient. Engineered for powder direct compression and dry granulation, its porous microstructure delivers excellent flow and compressibility, enabling tablets to disintegrate in the mouth in under 30 seconds without additional disintegrants. The natural mild sweetness and cooling sensation of mannitol provide effective taste-masking for bitter APIs. Suitable for pharmaceutical, OTC, nutraceutical, and food applications.

 

 

Product Feature

 

  • Spray-Dried Porous Spherical Particles
  • Excellent Powder Flowability
  • Superior Compressibility for Direct Compression
  • Rapid Self-Disintegration (<30 Seconds in Oral Cavity)
  • Natural Mild Sweetness with Cooling Sensation
  • Effective Taste-Masking for Bitter APIs
  • Simplified Formulation — Filler, Disintegrant & Flavoring in One
  • Reduced Process Steps & Lower Manufacturing Cost

 

 

Product Application

 

OPACT® Cornstarch Mannitol is primarily used in the production of orally disintegrating tablets (ODTs), where its rapid disintegration capability and pleasant mouthfeel make it an ideal excipient base. It is equally well suited to chewable tablets, pediatric formulations, and preparations containing bitter-tasting active ingredients. By enabling a pure direct-compression route, the product allows manufacturers to skip traditional wet granulation steps entirely—formulators simply blend the API with OPACT® Cornstarch Mannitol and a lubricant, then compress directly. This streamlined workflow is especially valuable for pharmaceutical companies seeking to accelerate product development, improve production efficiency, and reduce overall manufacturing costs.

 

 

Product Specification

 

Composition Loss on Drying (%) Bulk Density (g/ml)

Approx. 80% Mannitol; 

Approx. 20% Corn Starch

≤ 3.0 0.40-0.60

 

 

Packaging

 

  • 20-foot container can hold 10 to 11 metric tons of OPACT® Cornstarch Mannitol.
  • Standard packaging of 20/25 kg per bag.

 

 

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