OPACT® Cornstarch Mannitol is a co-processed pharmaceutical excipient manufactured by spray drying approximately 80% mannitol with 20% corn starch. It is designed as a direct-compression filler for orally disintegrating tablets and chewable tablets, delivering excellent powder flow, compressibility, and rapid disintegration.
Item No :
OPACT® Cornstarch MannitolProduct Origin :
CHINAShipping Port :
SHANG HAIPayment :
TT/LCWeight :
20/25KGOrder(MOQ) :
100KG
OPACT® Cornstarch Mannitol is a high-functionality co-processed excipient developed by Westpoint Pharma through a proprietary spray-drying process. By combining mannitol and corn starch at the sub-particle level, it forms porous spherical granules that integrate the functions of filler, disintegrant, and flavoring agent in a single ingredient. Engineered for powder direct compression and dry granulation, its porous microstructure delivers excellent flow and compressibility, enabling tablets to disintegrate in the mouth in under 30 seconds without additional disintegrants. The natural mild sweetness and cooling sensation of mannitol provide effective taste-masking for bitter APIs. Suitable for pharmaceutical, OTC, nutraceutical, and food applications.
OPACT® Cornstarch Mannitol is primarily used in the production of orally disintegrating tablets (ODTs), where its rapid disintegration capability and pleasant mouthfeel make it an ideal excipient base. It is equally well suited to chewable tablets, pediatric formulations, and preparations containing bitter-tasting active ingredients. By enabling a pure direct-compression route, the product allows manufacturers to skip traditional wet granulation steps entirely—formulators simply blend the API with OPACT® Cornstarch Mannitol and a lubricant, then compress directly. This streamlined workflow is especially valuable for pharmaceutical companies seeking to accelerate product development, improve production efficiency, and reduce overall manufacturing costs.
| Composition | Loss on Drying (%) | Bulk Density (g/ml) |
|---|---|---|
|
Approx. 80% Mannitol; Approx. 20% Corn Starch |
≤ 3.0 | 0.40-0.60 |