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RHEOL® HPMCP (Hypromellose Phthalate) is a white or off-white powder or granule with good flowability, odorless or with a slight acidic odor, and is nearly insoluble in water or absolute ethanol. RHEOL® HP50 is a grade of RHEOL® HPMCP, designed for enteric coating and controlled-release formulations with a dissolution pH of ≥5.0.
Item No :
RHEOL® HP50Product Origin :
CHINAShipping Port :
SHANG HAIPayment :
TT/LCWeight :
20/25KGOrder(MOQ) :
100KG
RHEOL® HP50 is specifically designed for enteric coating and pH-dependent drug delivery. It is suitable for organic solvent coating systems and offers good compatibility with active pharmaceutical ingredients (APIs). As an enteric coating, it remains intact in acidic gastric environments and dissolves in weakly alkaline intestinal environments, ensuring targeted drug release. It also functions effectively as a matrix material for sustained and controlled-release formulations. Since 1971, HPMCP has been widely used as an enteric coating cellulose derivative in the pharmaceutical industry.
RHEOL® HP50 is primarily utilized as an enteric coating material in the pharmaceutical industry, forming a flexible and tough film that resists rupture. This coating effectively protects acid-labile drugs from the acidic gastric juice and ensures the drug is released specifically in the intestinal tract where the pH is weakly alkaline. Additionally, it serves as a key excipient in sustained and controlled-release matrix systems, allowing for precise control over drug release rates and sites based on pH variations within the gastrointestinal tract. Its good compatibility with APIs and organic solvent systems makes it a versatile choice for capsule shells and advanced oral solid dosage forms.
| Viscosity (mPa·s) | Hydroxypropoxy (%) | Methoxy (%) |
|---|---|---|
| 44-66 | 6.0-10.0 | 20.0-24.0 |
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