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RHEOL® HPMC K Series (Hypromellose 2208) is a high-performance cellulose derivative used as a hydrophilic gel matrix material in pharmaceutical formulations. It ensures stable and controlled drug release in sustained-release tablets and capsules.
Item No :
RHEOL® K SeriesProduct Origin :
CHINAShipping Port :
SHANG HAIPayment :
TT/LCWeight :
20/25KGOrder(MOQ) :
100KG
Westpoint Pharma's RHEOL® HPMC K Series (Hypromellose 2208) includes four standard grades—XD-K100, XD-K4M, XD-K15M, and XD-K100M—plus an XD-K100M CR grade optimized for direct compression. Covering a wide viscosity range of 80–140,000 mPa·s (2% at 20°C), it provides flexible options for formulators. The K Series is engineered for high-speed direct compression, producing high-hardness tablets at lower main compression pressure to improve manufacturing efficiency and minimize weight variation.
RHEOL® HPMC K Series is predominantly utilized as a hydrophilic gel matrix material in controlled-release formulations, where it rapidly hydrates at body temperature to form a robust gel barrier that modulates drug diffusion and erosion for sustained therapeutic effects. This makes it the ideal choice for oral solid sustained and controlled-release preparations, ensuring consistent drug release profiles. Additionally, it functions effectively as a thickening and suspending agent in various pharmaceutical liquid and semi-solid formulations, providing reliable viscosity control.
| Model |
Viscosity (2% at 20°C, mPa·s) |
Methoxy (%) | Hydroxypropoxy (%) | Application |
|---|---|---|---|---|
| XD-K100 | 80-120 | 19.0-24.0 | 4.0-12.0 | Thickener, Suspending agent, CR |
| XD-K4M | 3,000-5,600 | 19.0-24.0 | 4.0-12.0 | Thickener, Suspending agent, CR |
| XD-K15M | 11,250-21,000 | 19.0-24.0 | 4.0-12.0 | Thickener, Suspending agent, CR |
| XD-K100M | 75,000-140,000 | 19.0-24.0 | 4.0-12.0 | Thickener, Suspending agent, CR |
| XD-K100M CR | 75,000-140,000 | 22.0-24.0 | 9.5-11.5 | Hydrophilic gel matrix (Optimized for direct compression) |
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